Publications

Acute and chronic hypoxia differentially predispose lungs for metastases.

Sci Rep. 2019 Jul 15;9(1):10246

Authors: Reiterer M, Colaço R, Emrouznejad P, Jensen A, Rundqvist H, Johnson RS, Branco C

Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging.

Cell Stem Cell. 2019 Sep 05;25(3):407-418.e6

Authors: Ho YH, Del Toro R, Rivera-Torres J, Rak J, Korn C, García-García A, Macías D, González-Gómez C, Del Monte A, Wittner M, Waller AK, Foster HR, López-Otín C, Johnson RS, Nerlov C, Ghevaert C, Vainchenker W, Louache F, Andrés V, Méndez-Ferrer S

Correlates of light physical activity among cancer survivors.

Psychooncology. 2019 04;28(4):726-734

Authors: Johnson RS, Fallon EA, Berg CJ

Hypoxia-inducible factor controls immunoregulatory properties of myeloid cells in mouse cardiac allografts - an experimental study.

Transpl Int. 2019 01;32(1):95-106

Authors: Keränen MAI, Raissadati A, Nykänen AI, Dashkevich A, Tuuminen R, Krebs R, Johnson RS, Syrjälä SO, Lemström KB

Glycolytic Response to Inflammation Over Time: Role of Myeloid HIF-1alpha.

Front Physiol. 2018;9:1624

Authors: Fitzpatrick SF, Gojkovic M, Macias D, Tegnebratt T, Lu L, Samén E, Rundqvist H, Johnson RS

Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.

Nat Commun. 2018 10 16;9(1):4181

Authors: Pitt JJ, Riester M, Zheng Y, Yoshimatsu TF, Sanni A, Oluwasola O, Veloso A, Labrot E, Wang S, Odetunde A, Ademola A, Okedere B, Mahan S, Leary R, Macomber M, Ajani M, Johnson RS, Fitzgerald D, Grundstad AJ, Tuteja JH, Khramtsova G, Zhang J, Sveen E, Hwang B, Clayton W, Nkwodimmah C, Famooto B, Obasi E, Aderoju V, Oludara M, Omodele F, Akinyele O, Adeoye A, Ogundiran T, Babalola C, MacIsaac K, Popoola A, Morrissey MP, Chen LS, Wang J, Olopade CO, Falusi AG, Winckler W, Haase K, Van Loo P, Obafunwa J, Papoutsakis D, Ojengbede O, Weber B, Ibrahim N, White KP, Huo D, Olopade OI, Barretina J

The role of Olfr78 in the breathing circuit of mice.

Nature. 2018 09;561(7724):E33-E40

Authors: Torres-Torrelo H, Ortega-Sáenz P, Macías D, Omura M, Zhou T, Matsunami H, Johnson RS, Mombaerts P, López-Barneo J

Transpl Int. 2019 01;32(1):95-106

Authors: Keränen MAI, Raissadati A, Nykänen AI, Dashkevich A, Tuuminen R, Krebs R, Johnson RS, Syrjälä SO, Lemström KB

HIF-2α is essential for carotid body development and function.

Elife. 2018 04 19;7:

Authors: Macias D, Cowburn AS, Torres-Torrelo H, Ortega-Sáenz P, López-Barneo J, Johnson RS

The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.

Cell Metab. 2018 04 03;27(4):898-913.e7

Authors: Sim J, Cowburn AS, Palazon A, Madhu B, Tyrakis PA, Macías D, Bargiela DM, Pietsch S, Gralla M, Evans CE, Kittipassorn T, Chey YCJ, Branco CM, Rundqvist H, Peet DJ, Johnson RS

Cancer Cell. 2017 11 13;32(5):669-683.e5

Authors: Palazon A, Tyrakis PA, Macias D, Veliça P, Rundqvist H, Fitzpatrick S, Vojnovic N, Phan AT, Loman N, Hedenfalk I, Hatschek T, Lövrot J, Foukakis T, Goldrath AW, Bergh J, Johnson RS

Cardiovascular adaptation to hypoxia and the role of peripheral resistance.

Elife. 2017 10 19;6:

Authors: Cowburn AS, Macias D, Summers C, Chilvers ER, Johnson RS

A Molecular Mechanism To Switch the Aryl Hydrocarbon Receptor from a Transcription Factor to an E3 Ubiquitin Ligase.

Mol Cell Biol. 2017 07 01;37(13):

Authors: Luecke-Johansson S, Gralla M, Rundqvist H, Ho JC, Johnson RS, Gradin K, Poellinger L

Hypoxia determines survival outcomes of bacterial infection through HIF-1alpha dependent re-programming of leukocyte metabolism.

Sci Immunol. 2017 Feb 10;2(8):

Authors: Thompson AA, Dickinson RS, Murphy F, Thomson JP, Marriott HM, Tavares A, Willson J, Williams L, Lewis A, Mirchandani A, Dos Santos Coelho P, Doherty C, Ryan E, Watts E, Morton NM, Forbes S, Stimson RH, Hameed AG, Arnold N, Preston JA, Lawrie A, Finisguerra V, Mazzone M, Sadiku P, Goveia J, Taverna F, Carmeliet P, Foster SJ, Chilvers ER, Cowburn AS, Dockrell DH, Johnson RS, Meehan RR, Whyte MK, Walmsley SR

Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis.

Biol Open. 2017 May 15;6(5):688-697

Authors: Evans CE, Palazon A, Sim J, Tyrakis PA, Prodger A, Lu X, Chan S, Bendahl PO, Belting M, Von Euler L, Rundqvist H, Johnson RS, Branco C

Cutaneous exposure to hypoxia does not affect skin perfusion in humans.

Acta Physiol (Oxf). 2017 07;220(3):361-369

Authors: Siebenmann C, Keramidas ME, Rundqvist H, Mijwel S, Cowburn AS, Johnson RS, Eiken O